Oxford University vaccine ‘safe’ and induces immune response, preliminary results show
- Credit: PA
A coronavirus vaccine being developed at the University of Oxford is safe and induces an immune reaction, preliminary results of the study show.
Researchers say their tests have revealed that the jab could provide double protection against Covid-19.
The early stage trial found that the vaccine is safe and causes few side effects.
It also induces strong immune responses in both parts of the immune system – provoking a T cell response within 14 days of vaccination, and an antibody response within 28 days.
Compared with the control group of those given a meningitis vaccine, the coronavirus vaccine caused minor side effects more frequently, according to the study.
You may also want to watch:
But some of these could be reduced by taking paracetamol, the researchers said, adding that there were no serious adverse events from the vaccine.
Co-author Professor Sarah Gilbert, of the University of Oxford, said: 'There is still much work to be done before we can confirm if our vaccine will help manage the Covid-19 pandemic, but these early results hold promise.
- 1 US election result could spark 'end of Brexit', claims peer
- 2 Brexiteer says EU 'spiteful' to end fast-track lanes for Brits after Brexit
- 3 'Assorted caviar' and 'board games' - Gifts confiscated from Boris Johnson due to anti-corruption laws
- 4 Farage says he can dodge US travel ban because he's a 'journalist'
- 5 Poll puts Labour on highest level of support since 2014
- 6 Question Time: Tory minister told 'diverse' cabinet doesn't erase race issues in party
- 7 Former Labour MP tells Jeremy Corbyn to retire after being suspended from party
- 8 Poll: Most Britons think Labour was right to suspend Jeremy Corbyn
- 9 Poll finds Boris Johnson key factor for Scots backing independence
- 10 Nigel Farage places £10,000 bet on Donald Trump to win second White House term
'As well as continuing to test our vaccine in phase three trials, we need to learn more about the virus – for example, we still do not know how strong an immune response we need to provoke to effectively protect against Sars-CoV-2 infection.
'If our vaccine is effective, it is a promising option as these types of vaccine can be manufactured at large scale.
'A successful vaccine against Sars-CoV-2 could be used to prevent infection, disease and death in the whole population, with high-risk populations such as hospital workers and older adults prioritised to receive vaccination.'
The current results focus on the immune response measured in the laboratory, and further testing is needed to confirm whether the vaccine effectively protects against infection.
An ideal vaccine against Sars-CoV-2 should be effective after one or two vaccinations and work in target populations including older adults and those with other health conditions, researchers say.
They add that it should confer protection for a minimum of six months, and reduce onward transmission of the virus to contacts.
However, the experts warn that the current trial, published in The Lancet, is too preliminary to confirm whether the new vaccine meets these requirements.
Phase two – in the UK only – and phase three trials to confirm whether it effectively protects against the virus are taking place in the UK, Brazil and South Africa.
Boris Johnson tweeted: 'This is very positive news. A huge well done to our brilliant, world-leading scientists & researchers at @UniofOxford.
'There are no guarantees, we're not there yet & further trials will be necessary – but this is an important step in the right direction.'
Health secretary Matt Hancock said the update on the vaccine was 'very encouraging news'.
He wrote: 'We have already ordered 100 million doses of this vaccine, should it succeed.
'Congratulations to the scientists at @UniofOxford & @OxfordVacGroup and leadership of @AstraZeneca.'
Become a Supporter
The New European is proud of its journalism and we hope you are proud of it too. We believe our voice is important - both in representing the pro-EU perspective and also to help rebalance the right wing extremes of much of the UK national press. If you value what we are doing, you can help us by making a contribution to the cost of our journalism.